TEST

SPECIFICATION

RESULTS

QUININE SULPHATE

CHARACTERS

Fine, silky needles, often in clusters, colorless

White Fine, silky needles, often in clusters, colorless

SPECIFIC OPTICAL ROTATION

-237°- -244°(c=2 chloroform)

-239°

IDENTIFICATION

1color reaction

positive

2color reaction

positive

positive

CHECK

Acidity  ph

5.7 6.6

Non solution substance in chloroformethanol

≤0.1%

<0.1%

Loss on drying

≤ 5.0%

3.9%

Residue on ignition

≤ 0.1%

0.08%

Assay

 (C₂₀H₂₄N₂O₂)2.H₂SO₄ 99.0%.

(calculated with reference to the dried substance)

99.7%

Conclusion

Conform  to  CP2005/ USP28